Complete the side-by-side record
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Compare in a fixed order
- Verify each study and local location.
- Compare what you could be assigned.
- Map procedures and time.
- Review risks, possible benefit, and alternatives with qualified people.
- Trace records, data, specimens, and results.
- Calculate expenses and accrued payment.
- Name every unanswered question.
Stop before ranking the studies when a medical or consent fact is missing. Convenience cannot resolve an unknown safety issue.
Write a decision statement
Complete this sentence for each study: “I would consider this study if ________ is confirmed, because the schedule and requirements fit ________, and I have discussed ________ with the study team or my clinician.”
Then write a refusal condition: “I would decline if ________.” A specific boundary works better than a total score that mixes unlike factors.
Sources for this guide
Official guidance controls regulatory claims. Peer-reviewed research is identified when participant experience requires evidence beyond agency guidance. Links were checked September 5, 2026.
- Office for Human Research Protections. Questions to Ask About Volunteering for a Research Study (opens in a new tab).
- ClinicalTrials.gov. How to Read a Study Record (opens in a new tab).
- National Institute on Aging. Clinical Research: Benefits, Risks, and Safety (opens in a new tab).
- U.S. Food and Drug Administration. Clinical Trial Participation (opens in a new tab).